Pushing back the cliff (but there probably still is a cliff): Arrhythmia, late outcome, and uncertainty in Fontan patients

Perspectives on the "generic cliff"--pushing and falling.

Wall Street health sector analyst Tim Anderson, MD, now at BernsteinResearch, called it the “generic cliff” in early 2007.1 From the perspective of brand-name pharmaceutical manufacturers and investors, the generic cliff is indeed formidable and often foreboding. What was a relatively gentle slope in erosion of the brand share of days of drug therapy when generic ranitidine entered the market i...

Cliff hangers

The peregrine falcon holds a special place in the minds of environmentalists and conservation biologists. The crash in its population throughout the 1950s and 60s was linked to the rapidly increasing use of agricultural organochlorine pesticides which led to a thinning of the birds’ eggshells and dramatic breeding failure. Since the widespread ban on the use of these chemicals, populations have...

Cliff hanger

The asparagus season has recently ended for northern hemisphere crops. Tradition has it that, at the summer solstice, growers stop cutting spears to allow the plant to grow and produce enough resources to generate spears for the next spring’s crop. The plant is becoming increasingly fashionable and production is increasing to meet demand. But the cultivated asparagus has a wild relative that is...

CLiFF Notes

The Cliff at the Border